L-165041 Size:Solid 10 mg (R)-1-(2-(2

(R)-1-(2-(2

CAS Number: 893990-34-6

PROTAC FKBP Degrader-3 is a potent FKBP degrader

It shows more than 100-fold selectivity for mTOR relative to PI3Kα

11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31

L-165041 Size:Solid 10 mg (R)-1-(2-(2L 165041, also known as L 165,041, is a potent and selective agonist of the nuclear receptor PPAR (Ki = 9 nM, EC50 = ~500 nM for hPPAR ). L 165041 promotes VEGF mRNA stabilization in HPV18 harboring HeLa cells through a receptor independent mechanism. L 165041 inhibits VEGF induced angiogenesis, but the antiangiogenic effect is not related to PPAR. L 165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell