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Romidepsin Catalog No.:M8157-10 Free Radic Res

SKU: 98226877813

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Romidepsin Catalog No.:M8157-10 Free Radic ResRomidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia induced angiogenesis and depletes several heat shock

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Description

Free Radic Res

HCQ treatment has been shown to cause increased apoptosis

p53 is not enzymatically degraded and the transcriptional activity of p53 is restored

GluR1 trafficking

is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production

Romidepsin Catalog No.:M8157-10 Free Radic ResRomidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia induced angiogenesis and depletes several heat shock

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