PROTAC BET degrader-3 ihydrochalcone Ishikawa tumors have higher apoptotic

Ishikawa tumors have higher apoptotic indices than Hec1A tumors after treatment with GSK2256098

2013 Nov 1

InChi: InChI=1S/C26H42N6O12S2/c1-13(2)8-17(26(43)44)32-24(41)15(4-5-20(35)36)30-25(42)18(11-45)29-19(34)10-27-22(39)16(9-21(37)38)31-23(40)14(28-12-33)6-7-46-3/h12-18

modified prothrombin time (mPT)

liver and non-small cell lung cancer tumors

PROTAC BET degrader-3 ihydrochalcone Ishikawa tumors have higher apoptoticPROTAC BET Degrader 3 is a potent BET degrader based on PROTAC. Product information Molecular Weight: 1045. 22 Formula: C53H64N12O9S Chemical Name: (2S, 4R) 1 [(2S) 2 (2 {2 [2 ({4 [(3 cyclopropyl 1 ethyl 1H pyrazol 5 yl)amino] 7 (3, 5 dimethyl 1, 2 oxazol 4 yl) 6 methoxy 9H pyrimido[4, 5 b]indol 2 yl}formamido)ethoxy]ethoxy}acetamido) 3, 3 dimethylbutanoyl] 4 hydroxy N {[4 (4 methyl 1, 3 thiazol 5 yl)phenyl]methyl}pyrrolidine 2 carboxamide Smiles: