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These include: Neurological symptoms : tingling or numbness in hands and feet (peripheral neuropathy), difficulty walking or balance problems, memory difficulties, or mood changes including depression Haematological signs : persistent fatigue, weakness, pale or jaundiced skin, or shortness of breath Glossitis : a sore, red, smooth tongue Cognitive symptoms : difficulty concentrating, confusion, or "brain fog" Seek urgent medical attention if you experience rapidly worsening neurological symptoms, significant difficulty walking, severe paraesthesia, or marked cognitive decline, as these may require immediate assessment

But with the extra receptors in the neuron connections (synaptic cleft), over-firing occurs

Deficiencies in B12 can lead to a host of problems, such as light-headedness, exhaustion, memory issues, and constipation

In the case of thin, crepey skin with many small wrinkles, the skin lacks its youthful support of collagen - and that can be corrected with collagen-induction therapies (there are non-invasive, non-surgical, and surgical options - generally speaking there is a trade-off between less invasive procedures needing more treatment sessions to achieve the same result as a more invasive procedure within this category of treatment)

The physical disruption denatures the protein irreversibly