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148 The senescence-associated secretory phenotype, characterized by the release of proinflammatory mediators, exacerbates chronic inflammation in muscle tissue, further impairing muscle repair and regeneration

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Supplementary Figure 3 Effects of ebselen on expressions of GPX2 and GPX4 in SGNs after peroxynitrite injury

How Epithalon Works: Mechanisms of Action Epithalons longevity-promoting effects come from several interconnected biological mechanisms: Activates telomerase maintains telomere length and cellular youthfulness Stimulates pineal gland increases melatonin production and regulates circadian rhythm Reduces oxidative stress neutralizes free radicals and DNA damage Normalizes immune activity promotes immune balance and thymus function Regulates gene expression modifies age-related gene activity via epigenetic pathways These systemic benefits help Epithalon restore balance in multiple organ systems at once