DUX4 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos and its expression and activation

and its expression and activation is associated with transformation and tumorigenesis

A similar protein in yeast is part of a two component methyltransferase| which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs

neurodegeneration

a reciprocal stimulation of cholesterol ester synthesis takes place

The encoded protein does not have a transmembrane domain

DUX4 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos and its expression and activationThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired like homeodomain