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However, given that this study did not measure IL-6 or IL-10, it is unclear where there was also a concomitant increase in anti-inflammatory molecular factors to counteract this response

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22,23 Other studies have shown no association of exercise with bone health

Therefore, the present study aimed to examine melatonins potential to alleviate central sensitization and nociplastic pain in a reserpine-induced FM model by restoring mitochondrial function and attenuating the consequent neuroinflammatory and glutamatergic disturbances in the spinal cord and DRG

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