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Trientine diHClide is another common copper chelator used for treating Wilson's disease (132), which can selectively bind Cu2+ ions to improve mitochondrial function in patients with hypertrophic cardiomyopathy (73), as well as restore mitochondrial function and normalize myocardial expression and enzymatic activity of proteins involved in energy metabolism among diabetic patients (133)

They are not intended to represent clinical evidence in humans, and AOD-9604 has not been approved by the FDA, EMA, or any other regulatory authority for any indication

Results depend strongly on the patient's natural skin phototype

Jennings L, Nestor L, Molloy O, et al

In view of the reports that, p53 is mutated and inactivated in 50% of all tumours, our observation that aspirin can acetylate mutant p53, is an important finding