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As a physician who prescribes GLP-1 medications like Ozempic, Wegovy, semaglutide, and tirzepatide, I explain why increasing your dose too quickly can affect muscle mass, metabolism, and long-term metabolic health

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But the really impressive numbers came from the SURPASS-5 trial, where tirzepatide reduced total cholesterol by 12.9%, LDL cholesterol by 15.5%, and triglycerides by a substantial 24.9%, while increasing HDL cholesterol by 0.9%

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