IKK Alpha Monoclonal Antibody, 50ul[BT-MCA0105] Enzyme Activity Assays Increased expression of this gene

Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed

and sequence variants of this gene are also associated with atrial fibrillation

An important paralog of this gene is SLC6A4

skeletal muscle

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily

IKK Alpha Monoclonal Antibody, 50ul[BT-MCA0105] Enzyme Activity Assays Increased expression of this geneThis gene encodes a member of the serine threonine protein kinase family. The encoded protein, a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.