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Separase Polyclonal Antibody, 50ul Hepatocytes GPS2 encodes G protein pathway

SKU: 3832315407

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Separase Polyclonal Antibody, 50ul Hepatocytes GPS2 encodes G protein pathwayStable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which

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Description

GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades

It is involved in inflammatory responses

SRPK3 encodes SRSF protein kinase 3 similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors

as well as regulate the expression of the tumorigenic protein CD44

suggesting that it is required for kinetochore formation

Separase Polyclonal Antibody, 50ul Hepatocytes GPS2 encodes G protein pathwayStable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which

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