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Rad17(Phospho Ser646) Polyclonal Antibody, 20ul Centrifuges Gene Ontology (GO) annotations related

SKU: 42001888582

4.4
PLN111.00 PLN155.00

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Rad17(Phospho Ser646) Polyclonal Antibody, 20ul Centrifuges Gene Ontology (GO) annotations relatedThe protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This

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Description

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled amine receptor activity

Alternatively spliced transcript variants of TNFRSF11B have been reported

Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6)

ARF4 is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D

neurotransmitter phenotype

Rad17(Phospho Ser646) Polyclonal Antibody, 20ul Centrifuges Gene Ontology (GO) annotations relatedThe protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This

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