FRS3 Polyclonal Antibody, 100ul Bottles Studies in rat indicate that

Studies in rat indicate that the protein is translated from a non-AUG translation initiation site

and is also a potent angiogenic factor

It is located within a homozygously deleted region of a metastatic prostate cancer

and also ovarian hyperstimulation syndrome

it does form heterodimers with other EGF receptor family members which do have kinase activity

FRS3 Polyclonal Antibody, 100ul Bottles Studies in rat indicate thatFRS3 encodes a substrate for the fibroblast growth factor receptor. Fibroblast growth factor receptor substrate 3 is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. Fibroblast growth factor receptor substrate 3 down regulates extracellular regulated kinase 2 through direct binding.