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SPIT2 Polyclonal Antibody, 20ul Low retention tips beta and gamma subunits are

SKU: 62429481737

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SPIT2 Polyclonal Antibody, 20ul Low retention tips beta and gamma subunits areThis gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster

This gene encodes a member of the acyl-Coenzyme A binding protein family| known to function in the transport and distribution of long chain acyl-Coenzyme A in cells

It also plays an important role in trafficking of T cells in thymus

tissue specificity:Seems to be expressed in prostate and less abundantly in adult brain

Plectin is a prominent member of an important family of structurally and in part functionally related proteins

SPIT2 Polyclonal Antibody, 20ul Low retention tips beta and gamma subunits areThis gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

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