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BRD2 Polyclonal Antibody, 50ul Cell Separation and Collection This protein is a nuclear

SKU: 6842657542

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BRD2 Polyclonal Antibody, 50ul Cell Separation and Collection This protein is a nuclearThis gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine 12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison

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Description

This protein is a nuclear phospho-protein

tissue specificity:Predominantly expressed in thymus

q12) with the pleiomorphic adenoma gene 1

The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme

This phosphorylation may play a role in RCC1 interaction with chromatin and its RanGEF activity

BRD2 Polyclonal Antibody, 50ul Cell Separation and Collection This protein is a nuclearThis gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine 12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison

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