JMJD2B Polyclonal Antibody, 50ul Sealing Film Vora (1981) [PubMed 6451249] determined
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JMJD2B Polyclonal Antibody, 50ul Sealing Film Vora (1981) [PubMed 6451249] determinedHistone demethylase that specifically demethylates 'Lys 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys 4', H3 'Lys 27', H3 'Lys 36' nor H4 'Lys 20'. Only able to demethylate trimethylated H3 'Lys 9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
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