GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 1038/nchembio

1038/nchembio

Rybczynska A

InChi: InChI=1S/C23H21ClN2O5/c1-30-22(28)14-9-7-13(8-10-14)21-20-16(15-5-3-4-6-17(15)25-20)11-18(23(29)31-2)26(21)19(27)12-24/h3-10

883065-90-5

etomoxir induces severe oxidative stress at commonly used concentrations

GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 1038/nchembioGNE 477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3K) and mTOR (apparent Ki = 21 nM). Product information CAS Number: 1032754 81 6 Molecular Weight: 504. 63 Formula: C21H28N8O3S2 Synonym: GNE477 GNE 477 Chemical Name: 5 {6 [(4 methanesulfonylpiperazin 1 yl)methyl] 7 methyl 4 (morpholin 4 yl)thieno[3,2 d]pyrimidin 2 yl}pyrimidin 2 amine Smiles: CC1C2=NC(=NC(=C2SC=1CN1CCN(CC1)S(C)(=O)=O)N1CCOCC1)C1=CN=C(N)N=C1 InChiKey: AKKCGLXULFRAET UHFFFAOYSA N