CUL-1 Polyclonal Antibody, 100ul[BT-AP08190] Metabolic enzymes tool compounds Mutations in or deletions of

Mutations in or deletions of the gene lead to growth hormone deficiency and short stature

through the regulatory roles of CDK4 and p53 in cell cycle G1 progression

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family

The protein is thought to be involved in Golgi-to-ER transport

Used for MX-RL-Pro

CUL-1 Polyclonal Antibody, 100ul[BT-AP08190] Metabolic enzymes tool compounds Mutations in or deletions ofCore component of multiple cullin RING based SCF (SKP1 CUL1 F box protein) E3 ubiquitin protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1 F box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin conjugating enzyme. The E3